Name: ARFGAP1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ARFGAP1抗原（重組蛋白）

英文名稱： ARFGAP1 Antigen (Recombinant Protein)

別名： ARF1GAP; HRIHFB2281

儲存： 冷凍（-20℃）

相關類別： 抗原

概述：

Fusion protein corresponding to a region derived from 279-406 amino acids of human ARFGAP1

技術(shù)規(guī)格：

Full name:	ADP-ribosylation factor GTPase activating protein 1
Synonyms:	ARF1GAP; HRIHFB2281
Swissprot:	Q8N6T3
Gene Accession:	BC028233
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

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