Name: BIRC7抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： BIRC7抗原（重組蛋白）

英文名稱： BIRC7 Antigen (Recombinant Protein)

別名： KIAP, LIVIN, MLIAP, RNF50, ML-IAP

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Full length fusion protein

技術規格

Full name:	baculoviral IAP repeat containing 7
Synonyms:	KIAP, LIVIN, MLIAP, RNF50, ML-IAP
Swissprot:	Q96CA5
Gene Accession:	BC014475
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

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