Name: MSLN抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： MSLN抗原（重組蛋白）

英文名稱： MSLN Antigen (Recombinant Protein)

別名： MPF; SMRP

儲存： 冷凍（-20℃）

相關類別：抗原

概述

Fusion protein corresponding to a region derived from 296-606 amino acids of human MSLN

技術規格

Full name:	mesothelin
Synonyms:	MPF; SMRP
Swissprot:	Q13421
Gene Accession:	BC009272
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a precursor protein that is cleaved into two products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiation factor functions as a cytokine that can stimulate colony formation in bone marrow megakaryocytes. Mesothelian is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants.

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