Name: UBQLN1抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：UBQLN1抗原（重組蛋白）

英文名稱： UBQLN1 Antigen (Recombinant Protein)

別名： DA41; DSK2; UBQN; XDRP1; PLIC-1

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 250 amino acids of human UBQLN1

技術(shù)規(guī)格：

Full name:	ubiquilin 1
Synonyms:	DA41; DSK2; UBQN; XDRP1; PLIC-1
Swissprot:	Q9UMX0
Gene Accession:	BC039294
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease.

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