Name: KIRREL2 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱： KIRREL2 抗原（重組蛋白）

英文名稱： KIRREL2 Antigen (Recombinant Protein)

別名：kirre like nephrin family adhesion molecule 2; NLG1; NEPH3; FILTRIN

儲存： 冷凍（-20℃）

相關類別： 抗原

概述

Fusion protein corresponding to C terminal 170 amino acids of human KIRREL2

技術規格

Full name:	kirre like nephrin family adhesion molecule 2
Synonyms:	NLG1; NEPH3; FILTRIN
Swissprot:	Q6UWL6
Gene Accession:	BC007312
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules. The encoded protein localizes to adherens junctions in pancreatic beta cells and regulates insulin secretion. Autoantibodies against the encoded protein have been detected in serum from patients with type 1 diabetes. This gene may also play a role in glomerular development and decreased expression of this gene has been observed in human glomerular diseases. This gene and the related opposite-strand gene nephrin (GeneID: 527362) are regulated by a bidirectional promoter.

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