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  • LRRC19 抗原(重組蛋白)

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    • 品牌 : 通蔚生物
    • 目錄號 : TW18262
    • 應(yīng)用 : 僅供科研使用
    • 貨期 : 現(xiàn)貨
    • 規(guī)格 :1mg/100ug
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中文名稱:  LRRC19 抗原(重組蛋白)

英文名稱: LRRC19 Antigen (Recombinant Protein)

別      名: leucine rich repeat containing 19

相關(guān)類別: 抗原

儲      存: 冷凍(-20℃) 

概      述

Fusion protein corresponding to a region derived from 171-370 amino acids of human LRRC19


技術(shù)規(guī)格

Full name:

leucine rich repeat containing 19

Swissprot:

Q9H756

Gene Accession:

BC126156

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

LRRC19 is a member of the extracellular leucine-rich repeat superfamily, a family of proteins that are thought to have diverse functions such as cell adhesion, signaling, and innate immunity. LRRC19 is closely related to the Toll-like receptors (TLRs), especially TLR3. LRRC19 does not contain a cytoplasmic Toll/IL-1 receptor (TIR) domain, but can activate NF-kappaB and induce the production of proinflammatory cytokines after stimulation with the TLR3 and other TLR ligands, suggesting that LRRC19 may play a role in the recognition and the response to certain pathogenic microorganisms. LRRC19 has also been suggested to be a potential biomarker for pancreatic tumor sensitivity to the anti-cancer, small molecule Src inhibitor AZD0530.


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