Name: MYOT抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：MYOT抗原（重組蛋白）

英文名稱： MYOT Antigen (Recombinant Protein)

別名： MFM3; TTID; TTOD; LGMD1; LGMD1A

儲(chǔ) 存： 冷凍（-20℃）

相關(guān)類別：抗原

概述：

Fusion protein corresponding to a region derived from 299-498 amino acids of human MYOT

技術(shù)規(guī)格：

Full name:	myotilin
Synonyms:	MFM3; TTID; TTOD; LGMD1; LGMD1A
Swissprot:	Q9UBF9
Gene Accession:	BC005376
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a cystoskeletal protein which plays a significant role in the stability of thin filaments during muscle contraction. This protein binds F-actin, crosslinks actin filaments, and prevents latrunculin A-induced filament disassembly. Mutations in this gene have been associated with limb-girdle muscular dystrophy and myofibrillar myopathies. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

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