Name: PSMB10 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：PSMB10 抗原（重組蛋白）

英文名稱： PSMB10 Antigen (Recombinant Protein)

別名： proteasome subunit beta 10; LMP10; MECL1; beta2i

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to a region derived from 40-273 amino acids of human PSMB10

技術(shù)規(guī)格：

Full name:	proteasome subunit beta 10
Synonyms:	LMP10; MECL1; beta2i
Swissprot:	P40306
Gene Accession:	BC017198
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.

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