Name: ANAPC5 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：ANAPC5 抗原（重組蛋白）

英文名稱： ANAPC5 Antigen (Recombinant Protein)

別名： anaphase promoting complex subunit 5; APC5

儲存： 冷凍（-20℃）

相關(guān)類別： 抗原

概述：

Fusion protein corresponding to C terminal 300 amino acids of human ANAPC5

技術(shù)規(guī)格：

Full name:	anaphase promoting complex subunit 5
Synonyms:	APC5
Swissprot:	Q9UJX4
Gene Accession:	BC006301
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene.

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