Name: TSLP 抗原（重組蛋白）
Brand: 通蔚生物

中文名稱：TSLP 抗原（重組蛋白）

英文名稱： TSLP Antigen (Recombinant Protein)

別名： Thymic stromal lymphopoietin

儲存： 冷凍（-20℃）

相關類別：抗原

概述：

Fusion protein corresponding to a region derived from 100-159 amino acids of human TSLP

技術規格：

Full name:	Thymic stromal lymphopoietin
Swissprot:	Q969D9
Gene Accession:	BC016720
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.

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