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Background: |
This gene encodes the interleukin-1 receptor-associated kinase 1, one of two putative serine/threonine kinases that become associated with the interleukin-1 receptor (IL1R) upon stimulation. This gene is partially responsible for IL1-induced upregulation of the transcription factor NF-kappa B. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
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Applications: |
IHC |
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Name of antibody: |
IRAK1(Phospho-Ser376) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 376(Q-S-S(p)-M-V) derived from Human IRAK1. |
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Full name: |
interleukin-1 receptor-associated kinase 1 |
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Synonyms: |
IRAK; pelle |
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SwissProt: |
P51617 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |

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